Vol. 42 (2): 188-198, March – April, 2016

doi: 10.1590/S1677-5538.IBJU.2015.0365


Overactive bladder – 18 years – Part I

Jose Carlos Truzzi 1, Cristiano Mendes Gomes 2, Carlos A. Bezerra 3, Ivan Mauricio Plata 4, Jose Campos 5, Gustavo Luis Garrido 6, Fernando G. Almeida 1, Marcio Augusto Averbeck 7, Alexandre Fornari 8, Anibal Salazar 9, Arturo Dell’Oro 10, Caio Cintra 3, Carlos Alberto Ricetto Sacomani 9, Juan Pablo Tapia 11, Eduardo Brambila 12, Emilio Miguel Longo 13, Flavio Trigo Rocha 2, Francisco Coutinho 12, Gabriel Favre 14, José Antonio Garcia 14, Juan Castaño 15, Miguel Reyes 12, Rodrigo Eugenio Leyton 16, Ruiter Silva Ferreira 17, Sergio Duran 12, Vanda López 18, Ricardo Reges 19

1 Escola Paulista de Medicina – EPM – Universidade Federal de São Paulo, SP, Brasil; 2 Departamento de Urologia, Universidade de São Paulo, SP, Brasil; 3 Departamento de Urologia, Faculdade de Medicina do ABC, SP, Brasi; 4 Departamento de Urología, Universidad de los Andes, Bogota, Colombia; 5 Departamento de Urología, Escuela Médico Militar, Cidade do México, Mexico; 6 Cátedra de Urologia, Hospital de Clínicas “José de San Martín”, Buenos Aires, Argentina; 7 Departamento de Urologia, Mãe de Deus Center Hospital, Porto Alegre, RS, Brasil; 8 Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, RS, Brasil; 9 Departamento de Urologia, AC Camargo Hospital, SP, Brasil; 10 Hospital Clinico de la Fuerza Area de Chile, Santiago, Chile; 11 Instituto Mexicano del Seguro Social, Ciudad de Mexico, Mexico; 12 Departamento de Urologia, Hospital Souza Aguiar, RJ, Brasil; 13 Servicio de Urología, del Complejo Médico Policial Churruca Visca, Buenos Aires, Argentina; 14 Centro Policlínico Valencia “La Viña”, Valencia, Venezuela; 15 Hospital Pablo Tobón Uribe, Medellin, Colômbia; 16 Servicio de Urología, Clinica Indisa, Providencia, Chile; 17 Centro de Reabilitação e Readaptação Dr. Henrique Santillo, Goiânia, Brasil; 18 Servicio de Urología, del Hospital Universitario de Caracas, Caracas, Venezuela; 19 Divisão de Urologia, Universidade Federal do Ceará, CE, Brasil


Overactive bladder syndrome is one of the lower urinary tract dysfunctions with the highest number of scientific publications over the past two decades. This shows the growing interest in better understanding this syndrome, which gathers symptoms of urinary urgency and increased daytime and nighttime voiding frequency, with or without urinary incontinence and results in a negative impact on the quality of life of approximately one out of six individuals – including both genders and almost all age groups. The possibility of establishing the diagnosis just from clinical data made patients’ access to specialized care easier. Physiotherapy resources have been incorporated into the urological daily practice. A number of more selective antimuscarinic
drugs with consequent lower adverse event rates were released. Recently, a new class of oral drugs, beta-adrenergic agonists has become part of the armamentarium for Overactive Bladder. Botulinum toxin injections in the bladder and sacral neuromodulation are routine modalities of treatment for refractory cases. During the 1st Latin-American Consultation on Overactive Bladder, a comprehensive review of the literature related to the evolution of the concept, epidemiology, diagnosis, and management was conducted. This text corresponds to the first part of the review Overactive Bladder 18-years.

Keywords: Overactive Bladder; Muscarinic Antagonists; Beta-adrenergic agonists; Botulinum Toxin; Sacral neuromodulation; Urodynamics

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