Vol. 43 (6): 1136-1143, November – December, 2017

doi: 10.1590/S1677-5538.IBJU.2016.0005

ORIGINAL ARTICLE
Lucio Dell’Atti 1

1 Department of Urology, University Hospital “St.Anna”, Ferrara, Italy

ABSTRACT

Purpose: We evaluated the correlation between prostate calculi and hematospermia in patients undergoing prostate biopsy, and its impact on sexual activity of patients.

Materials and Methods: A single-center prospective randomized study of 212 patients referred for transrectal ultrasound-guided prostate biopsy (TRUSBx) was performed. All patients were divided into two groups: Group A (GA), 106 patients with moderate/ marked presence of prostatic calculi visualized by TRUS; Group B (GB), 106 patients with absence/scarce of prostatic calcifications. Patients were handed questionnaires to obtain a validated data on the duration and impact of hematospermia on sexual activ­ity. The anxiety scores were recorded using a visual analogue scale.

Results: No significant difference was noted between the two groups when comparing age, preoperative PSA level, prostate volume, and biopsy number, except for digital rectal examination (DRE) findings. Post-biopsy results of patients included in GA re­vealed that the complication of hematospermia was present in 65.1%, while in GB was present in 39.7% (p<0.001).

On multivariate analysis for identifying significant preoperative predictors of hemato­spermia, which included variables of age, PSA, prostate volume, and prostate cancer were not shown to be significant predictors of hematospermia, except DRE and pros­tate calculi (p<0.001).

The mean anxiety score was 3.7±2.8 in GA and 2.3±1.9 in GB, respectively (p<0.001).

Conclusions: Prostatic calculi are an independent predictive factor of severe hemato­spermia after TRUSBx on the basis of multivariate analysis, but don’t affect the posi­tive rate of prostate cancer. Patients should be adequately counselled before TRUSBx to avoid undue anxiety and alterations in sexual activity.

Keywords: Prostate; Ultrasound, High- Intensity Focused, Transrectal; Biopsy; Hemospermia

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